What RX Depletes What?
Many common prescriptions do their job—but can quietly drain vitamins and minerals that power energy, mood, hormones, and longevity. This article maps key drug–nutrient depletions (from statins and birth control to antibiotics, acid blockers, pain relievers, and metformin), why they matter, and practical ways to rebuild with diet, supplements, and microbiome support. Educational only—consult your clinician before making changes.
WELLNESS
Did You Know Your Meds Might Be Depleting Nutrients?
Many common prescriptions do their job, but they can also drain your body of essential vitamins and minerals needed for energy, immunity, hormone balance, and longevity.
Here’s a breakdown:
Statins (Cholesterol Drugs)
Deplete:CoQ10, Vitamin D, Selenium
Why it matters:CoQ10 is critical for heart and muscle energy & low levels can lead to fatigue, muscle pain, and brain fog.
Birth Control Pills
Deplete: B2, B6, B12, Folate, Magnesium, Zinc, Selenium, Vitamin C
Why it matters:These nutrients support mood, metabolism, and hormone detox. Deficiency can cause PMS, low energy, and anxiety.
Antidepressants (SSRIs, Tricyclics)
Deplete:CoQ10, Melatonin, B-vitamins, Magnesium, and sometimes Sodium
Why it matters: These support serotonin and mitochondrial function and low levels may worsen fatigue or sleep issues.
Antibiotics
Deplete:B-vitamins (especially B1, B2, B6, B12, K2) and beneficial gut flora
Why it matters:Gut bacteria make vitamins and regulate your immune system — always rebuild your microbiome after antibiotic use!
Acid Blockers (PPIs & H2 Blockers like Prilosec, Nexium, Pepcid)
Deplete: B12, Magnesium, Calcium, Iron, Zinc
Why it matters: Stomach acid is needed to absorb minerals long-term use can lead to weakness, anemia, or even bone loss.
Blood Pressure Medications
Deplete: CoQ10, Zinc, Magnesium, Potassium (esp. diuretics)
Why it matters: Electrolyte imbalance can cause fatigue, cramps, or irregular heartbeat.
Pain Relievers (NSAIDs like Ibuprofen, Naproxen)
Deplete:Folate, Iron, Vitamin C
Why it matters: Chronic use irritates the gut lining, leading to reduced nutrient absorption and potential anemia.
Aspirin
Deplete:Vitamin C, Iron, Folate, Potassium, and sometimes Zinc
Why it matters: Over time, these deficiencies can impact healing and energy.
Arthritis Medications (Corticosteroids & Methotrexate)
Deplete:Calcium, Magnesium, Potassium, Vitamin D, Folate, and Zinc
Why it matters: Can lead to bone loss, fatigue, and immune weakness.
Diabetes Drugs (Metformin)
Deplete: B12, Folate, CoQ10
Why it matters: These nutrients protect nerve and brain health — low levels can cause numbness or cognitive issues.
The Takeaway:
Medications can help but nutrients save your life! If you’re on long-term prescriptions, work to look how to replenish what your body loses.
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